Last time when top seeds from men and women side lost on the same day:
On September 6 , 2003 Kim Clijsters (No.1) lost vs. Justine Henin in the final of US Open.
On September 6, 2003 Andre Agassi (No.1) lost vs. Juan Carlos Ferrero in the semifinal of the Super Saturday.
Last time when top seeds from men and women side lost on the same day before the final:
On July 3, 1974 in Wimbledon Billie Jean King (No.1) lost vs. Olga Morozova in the QF.
On July 3, 1974 in Wimbledon John Newcombe (No.1) lost vs. Ken Rosewall in the QF.
It was the first time since the French Open in 2010 that both top-seeded players went out in the same round. In the quarterfinals at Roland Garros that year, Roger Federer lost to Robin Soderling and Serena Williams lost to Sam Stosur.